American Trypanosomiasis, also recognized as Chagas disease, is a life-threatening zoonotic disease caused by the parasite Trypanosoma cruzi. World Chagas Disease Day is seen on April 14; to increase awareness concerning Chagas disease. The substantial manners of transmission are by blood transfusion and the bite of the reduviid bug. The organism lives in three morphological shapes: trypomastigotes, amastigotes, as well epimastigotes. In common, Chagas disease is most viewed in the southern United States, Central and South America, and Trinidad. 

However, pharmacotherapy remains a prime requirement for the treatment of Chagas illness, making this a prime topic for implying on the public health schedule of pharmacists. As experts in medication treatment, pharmacists require to connect with other colleagues in the fight versus this neglected illness. Moreover, pharmaceutical care is the immediate interaction between patient and pharmacist; to develop therapeutic compliance; develop quality of life; as well encourage appropriate pharmacotherapeutic follow-up. Pharmacists should struggle to recognize patients who may take a benefit from therapy, advocate novel medication improvement, as well develop arrival to existing treatments.